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In Brief This Week: Cofactor Genomics, Knome; Rosetta Genomics; Eagle Genomics; BioServe, UMass

By a GenomeWeb staff reporter

NEW YORK (GenomeWeb News) – Cofactor Genomics said this week that it has installed an Applied Biosystems SOLiD 4 sequencer and plans to use the instrument to sequence the genome of British heavy metal legend Ozzy Osbourne. The sequencing services provider will construct and sequence DNA libraries, while direct-to-consumer genome analysis firm Knome will analyze and interpret the data.

Rosetta Genomics said this week that Clalit Health Services, Israel's largest and the world's second-largest HMO, has established reimbursement coverage for its miRview mets test. It said that, initially, reimbursement will be provided to patients participating in a clinical study being conducted at three medical centers in Israel, with plans to expand reimbursement for the test to all Clalit members. The miRview mets test is a microRNA-based test used to assign a primary site to metastases in cases where the physician is unsure of its origin.

Eagle Genomics this week announced that it will provide bioinformatics services to OneNucleus, a newly created regional membership organization formed through the merger of ERBI and the London Biotechnology Network. Eagle will offer genome data management and integration services to OneNucleus' more than 500 members.

BioServe will supplement its own Global BioRepository with biospecimen samples from the University of Massachusetts Medical School's Cancer Center Tissue Bank, which has tissues and other samples from more than 20 different cancer types.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.