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In Brief This Week: Bruker; Thermo Fisher; Quest; Shimadzu; CombiMatrix; Diaxonhit; The Parent Project Muscular Dystrophy; Eastern Biotech & Life Sciences; Macrogen

NEW YORK (GenomeWeb News) – Bruker this week opened Centers of Excellence in Mumbai and Bengaluru, India. The two centers will provide Bruker customers access to multi-technology applications, training, and demonstration capabilities, the company said. It will also support research collaborations between Bruker and key customers in India. Bruker said it expects $50 million in revenues in India and to employ 100 people in the country in 2013.

Thermo Fisher Scientific declared a quarterly cash dividend of $.015 per share. The dividend will be paid on April 15 to shareholders of record as of March 15.

Quest Diagnostics declared a quarterly cash dividend of $.30 per share to be paid on April 16 to shareholders of record as of April 2.

Shimadzu Scientific Instruments is providing $7.5 million to the University of Texas at Arlington to support the installments of advanced scientific equipment. It is the largest philanthropic gift in the university's history, it said, and the Institute for Research Technologies at UT will be renamed the Shimadzu Institute for Research Technologies. It houses $25.2 million in equipment from Shimadzu.

A year ago, the company and the university partnered to create the Shimadzu Center for Advanced Analytical Chemistry, then partnered again in the fall to create the Institute for Research Technologies.

CombiMatrix on Feb. 26 entered into an Amendment No. 1 to common stock purchase warrants with each holder of certain of the firm's warrants to purchase up to an aggregate of 939,260 shares of CombiMatrix's common stock. The warrants were originally issued on Oct. 1, 2012 and Dec. 6, 2012 and were not exercisable for the first six months following the applicable issue date of each warrant.

On Feb. 22, the company board approved amending each warrant to allow each warrant to be immediately exercisable in full. The warrants, as a result, became exercisable in full as of Feb. 22.

Diaxonhit announced the French Blood Bank has awarded InGen four national public tenders to supply the blood bank with tests necessary to perform HLA typing and monitoring in the field of transplantation. InGen is a marketing affiliate of Diaxonhit, which was formed when Exonhit acquired InGen in November. The tenders are for four years and potentially can generate revenues of up to €13.8 million ($17.9 million) by the end of 2016.

The Parent Project Muscular Dystrophy is providing $100,000 to Stanley Nelson at the University of California, Los Angeles to analyze the genomes of 40 boys with Duchenne muscular dystrophy in order to identify genes other than dystrophin that may affect the course of the disease. The boys whose genomes are being examined are either very mildly affected or severely affected. Nelson will perform exome sequencing for his work.

Eastern Biotech & Life Sciences opened its first overseas office recently. The office is located in Muscat, Oman. Based in Dubai, United Arab Emirates, Eastern Biotech provides genetic testing and counseling and other diagnostic services to the healthcare community in the Middle East.

Macrogen has launched its Macrogen Clinical Laboratory in Rockville, Md. The firm provides sequencing services to the biotechnology and research community and said that it anticipates receiving CLIA certification and offering clinical diagnostic sequencing "within the coming months."

In Brief This Week is a Friday column containing news items that our readers may have missed during the week.

The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.

Genome-Wide Analysis Sheds Light on Genetics of ADHD

A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.

MicroRNA Cotargeting Linked to Lupus

A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus.

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.