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In Brief This Week: Bio-Rad Laboratories; TGen, Van Andel Research Institute; Infosys, Elan; Dotmatix, Boehringer Ingelheim

By a GenomeWeb staff reporter

NEW YORK (GenomeWeb News) – Bio-Rad Laboratories has completed its offer to exchange up to $300 million aggregate principal amount of its 8 percent Senior Subordinated Notes due 2016 for any and all of its outstanding 8 percent Senior Subordinated Notes due 2016 that were issued in a private placement. All of the notes were tendered before the deadline yesterday.


The Translational Genomics Research Institute (TGen) said that it has completed the strategic alliance and affiliation agreement with the Van Andel Research Institute initially signed early last year. TGen, which is a non-profit biomedical research organization, and VARI formed the alliance to combine VARI's basic research knowledge with TGen's translational genomics and analysis capabilities to further studies of diseases such as cancer, neurological disorders, diabetes, and infectious diseases.


Infosys said that it will design and implement a research informatics system at Elan Pharmaceuticals to accelerate discovery research. Infosys said that future versions of the software may enable integration of the system with electronic lab notebook and analytical dashboards to bring about more efficient research knowledge.


Dotmatix said that Boehringer Ingelheim has licensed its Browser and Vortex bioinformatics tools. BI will use the products to query, browse, and analyze key drug discovery information across research programs and project teams, said Dotmatix.


TTP LabTech this week launched its new contract screening service based on its Acumen microplate cytometer. "The service will provide clients with high-content data using cell-based assays for the investigation of various biological phenomena — including cell cycle, RNAi profiling, angiogenesis, and signal pathway profiling," TTP said in a statement.

The Scan

Ancient Greek Army Ancestry Highlights Mercenary Role in Historical Migrations

By profiling genomic patterns in 5th century samples from in and around Himera, researchers saw diverse ancestry in Greek army representatives in the region, as they report in PNAS.

Estonian Biobank Team Digs into Results Return Strategies, Experiences

Researchers in the European Journal of Human Genetics outline a procedure developed for individual return of results for the population biobank, along with participant experiences conveyed in survey data.

Rare Recessive Disease Insights Found in Individual Genomes

Researchers predict in Genome Medicine cross-population deletions and autosomal recessive disease impacts by analyzing recurrent nonallelic homologous recombination-related deletions.

Genetic Tests Lead to Potential Prognostic Variants in Dutch Children With Dilated Cardiomyopathy

Researchers in Circulation: Genomic and Precision Medicine found that the presence of pathogenic or likely pathogenic variants was linked to increased risk of death and poorer outcomes in children with pediatric dilated cardiomyopathy.