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In Brief This Week: AB Sciex; BioServe; Cellectis Plant Sciences; Cylene Pharmaceuticals, Horizon Discovery; GeneWiz; SeqGen, Illumina

By a GenomeWeb staff reporter

NEW YORK (GenomeWeb News) – The US Food and Drug Administration has purchased eight AB Sciex QTrap 5500 Systems for use at its headquarters and seven field labs for analysis of the US food supply, AB Sciex said this week.

BioServe said this week that the Maine Medical Center's Tissue Bank has joined the BioServe Network, a collection of research and medical institutes that provide biomaterials for a biorepository run by the firm.

Cellectis Plant Sciences, the plant genome engineering subsidiary of French firm Cellectis, has licensed rights to Midwest Oilseeds' Aerosol Beam Injector technology for precise modification of plant genomes. The technology allows functional meganucleases to be delivered directly into plant cells, thus avoiding the need for DNA vectors.

Cylene Pharmaceuticals will use Horizon Discovery's X-Man human isogenic cancer cell lines to identify patients who will respond to its CK2 inhibitor, CX-4945, which is currently in Phase I studies. The San Diego-based biopharmaceutical company is developing the kinase inhibitor for treatment of multiple myeloma.

Genewiz said this week that it has expanded its DNA sequencing capabilities with the opening of a new lab in Cambridge, Mass. The South Plainfield, NJ-based firm said that the new lab will offer a variety of sequencing services, as well as gene synthesis, molecular biology, and other genomic services.

Torrance, Calif.-based SeqGen has signed an agreement to become an instrument service provider for Illumina's NexGen GAIIx analyzers.

The Scan

Study Follows Consequences of Early Confirmatory Trials for Accelerated Approval Indications

Time to traditional approval or withdrawal was shorter when confirmatory trials started prior to accelerated approval, though overall regulatory outcomes remained similar, a JAMA study finds.

Sequencing Study Leads to Vaccine Target in Bacteria Behind Neonatal Meningitis

Researchers eBioMedicine track down potential vaccine targets with transposon sequencing on mutant bacteria causing neonatal meningitis in mouse models of the disease.

Multiple Myeloma Progression Influenced by Immune Microenvironment Expression

Researchers in NPJ Genomic Medicine compare RNA sequencing profiles of 102,207 individual cells in bone marrow samples from 18 individuals with rapid or non-progressing multiple myeloma.

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.