Clinical Sequencing | GenomeWeb

Clinical Sequencing

The Genome Institute of Singapore will collaborate with the new center to develop applications related to cancer diagnosis and treatment stratification.

Multiple molecular disease diagnoses were made in nearly 5 percent of individuals where exome sequencing was informative.

Under the agreement, Roche Diagnostics will offer Good Start's GeneVu carrier screening test along with its Harmony NIPT.

The study is the first published data of BGI's desktop sequencer, BGISEQ-500, which German researchers are studying for use in evaluating microRNA biomarkers. 

The researchers will sequence the genomes and transcriptomes of 250 breast cancer patients in the first phase, returning information from 16 actionable genes. 

Identification of DNA fragments and structural variations
Compositions and methods for detecting allelic variants
Method of DNA sequencing by hybridisation
Method of sequence determination using sequence tags
Methods for high fidelity production of long nucleic acid molecules
Chin set-up and high accuracy nucleic acid sequencing