Biomarker Discovery & Validation

The grant will fund a collaboration investigating whether genomic signatures and other biomarkers can be used in clinical diagnosis and monitoring of kidney cancer.

The collaborators are each providing funding and samples, and plan to study about 100 patients with a subset of Castleman disease to identify biomarkers.

Cancer Genetics will help analyze biomarkers to identify response patient populations, as well as reflect the mechanism of action of Effector's eFT508.

Poly(GP) proteins could be detected within ALS patients samples and used to determine whether ALS drugs under development are reaching their targets.

Researchers hope to identify exosomal biomarkers that can predict or detect cancer recurrence and metastasis at its earliest stages.

Biomarker method
DACH1 as a biomarker for diabetes
Gene methylation as a biomarker in sputum
Biomarker analysis using scodaphoresis
Methods and biomarkers for detection and prognosis of cervical cancer
Serum MG53 as a diagnostic marker for tissue injury

A fire at a Manchester hospital may have destroyed lab equipment and data, the Guardian reports.

Researchers generate a genetic database from skeletal remains from the 1845 Franklin Expedition to the Arctic, Live Science reports.

Researchers in China have begun another trial using CRISPR/Cas9 approaches in cancer patients, according to the Wall Street Journal.

In Science this week: human DNA found in sediments from archeological sites lacking bones, and more.