Clinical Sequencing

News on sequencing-based testing, NGS gene panels, & diagnostic exomes in genetics, genomics, and molecular diagnostics.

Investigators studied 442 patients with CUP and found mutations that could inform a specific treatment decision in more than half of them.

The SPRING trial is exploring a three-drug strategy, starting with Ibrance, Inlyta, and Bavencio, and will validate a biomarker algorithm for predicting responders.


The researchers plan to work with the NIH's Genome Research Alliance for Transplantation consortium to compare their method with others.

The company reported $35.0 million in revenues, driven by higher adoption of its molecular information solutions. 

The company is collaborating with hospitals to implement sequencing and machine learning approaches to pinpoint the molecular etiology of autism earlier in age.

Base-by-base ratcheting of DNA/RNA in a Y-shaped nanochannel
Identification of DNA fragments and structural variations
Compositions and methods for detecting allelic variants
Method of DNA sequencing by hybridisation
Method of sequence determination using sequence tags
Methods for high fidelity production of long nucleic acid molecules

Jay Shendure and his colleagues have developed a new method to more comprehensively identify human cell types, the NY Times reports.

Researchers in the UK and Japan have shown that infertility in mice with three sex chromosomes can be overcome, according to the Guardian.

China is embracing preimplantation genetic diagnosis, Nature News reports. 

In PLOS this week: host genetic factors associated with cervical neoplasia progression, population patterns for an ancient flowering rainforest plant, and more.

Sep
27
Sponsored by
Philips Genomics

This webinar will present an in-depth look at how Memorial Sloan Kettering Cancer Center has developed and implemented a next-generation sequencing panel for mutational tumor profiling of advanced cancer patients.

Sep
28
Sponsored by
Fabric Genomics

This webinar will discuss the critical role that software can play for clinical labs looking to establish comprehensive genomic testing programs.