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SeqWright to Offer RainDance Microdroplet PCR with Sequencing Services


SeqWright said this week that it plans to offer targeted sequencing services based on RainDance Technologies' microdroplet-based PCR technology.

RainDance's Rainstorm sequence-enrichment application provides the "sensitivity and specificity of gold-standard PCR in a novel microdroplet-based format that avoids the limitations of traditional multiplex amplification or hybridization-capture methods," SeqWright said in a statement.

The RainStorm microdroplet-based technology allows researchers to amplify up to 20,000 genomic loci with high specificity and uniformity, "allowing them to greatly reduce study time, or to improve study quality by running more samples in the same time within the same experimental budget," SeqWright said.

In addition to SeqWright, several other sequencing service providers offer target amplification on the RainDance platform, including Expression Analysis, Ambry Genetics, the National Center for Genome Resources, and Atlas Biolabs.

In a study published in Nature Biotechnology last November, researchers from the Scripps Translational Science Institute; the University of California, San Diego School of Medicine; and RainDance compared the Rainstorm technology to other enrichment methods and determined that "microdroplet PCR generates substantially greater uniform coverage of targeted sequences."

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