Skip to main content
Premium Trial:

Request an Annual Quote

NuGen, Advanced Liquid Logic to Co-Develop NGS Sample Prep Automation Technology


NuGen and Advanced Liquid Logic will co-develop automated sample prep technology for next-generation sequencing, the companies said today.

Under the exclusive co-development and supply agreement, Advanced Liquid Logic will provide instrumentation, software, and digital microfluidics cartridge technology to NuGen for commercialization.

Advanced Liquid Logic's benchtop system includes a disposable cartridge that can be configured for multiple different sample prep applications, according to the company.

The companies plan to co-develop a system, which NuGen will market, called Mondrian, with an initial focus on next-gen sequencing library prep protocols for Illumina sequencing platforms.

NuGen is currently collaborating with the Broad Institute to develop the first protocols. It is also planning to develop its Ovation RNA-seq and Encore Amplification Free NGS Library System on the Mondrian, and expects those to be available by the end of the year.

NuGen's technology has to date been focused on allowing researchers to work with small amounts of starting material, said CEO Elizabeth Hutt in a statement. "Introduction of this system is a natural extension of that mission, as the system allows for even smaller amounts of starting materials by working in volumes unachievable with any other existing technologies."

The Scan

UK Team Presents Genetic, Epigenetic Sequencing Method

Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers.

DNA Biobank Developed for French Kidney Donors, Recipients

The KiT-GENIE biobank described in the European Journal of Human Genetics contains DNA samples, genotyping profiles, immune patterns, and clinical features for thousands of kidney donors or transplant recipients in Nantes, France.

Cardiometabolic Disease May Have Distinct Associations With Microbial Metabolites in Blood, Gut

By analyzing gut microbes in combination with related metabolites in feces and blood, researchers in Nature Communications found distinct cardiometabolic disease relationships at each site.

Study Reveals New Details About Genetics of Major Cause of Female Infertility

Researchers in Nature Medicine conducted a whole-exome sequencing study of mote than a thousand patients with premature ovarian insufficiency.