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New Products: SoftGenetics' Floton; GenBank

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SoftGenetics has developed Floton, an assembly algorithm for Ion Torrent PGM paired-end sequencing data (see story, this issue). The assembler converts Ion Torrent data into "flow call" data, which helps correct for homopolymer errors and speeds up assembly, according to the company. An application note is available via the Ion Torrent website.


GenBank release 187.0 is available here via FTP from the National Center for Biotechnology Information. It contains data as of Dec. 15.

The new release comprises approximately 135 gigabases of data from 146 million entries of non-whole genome sequencing, non-CON sequences, and around 240 gigabases from 74 million entries from whole-genome sequences. Uncompressed, the release 187.0 flatfiles require around 518 gigabases of sequence files only.

Since the previous release in August, the non-WGS/non-CON portion grew by 3.1 gigabases, increasing the number of entries by 2 million. An additional 1.6 million records were updated.

The Scan

Another Resignation

According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug.

Novavax Finds Its Vaccine Effective

Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19.

Can't Be Used

The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports.

PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More

In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.