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New Products: NuGen's Encore NGS Library Systems; Bioo's Nextflex ChIP-seq; dbSNP 135; Galaxy

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NuGen and Ion Torrent have released the NuGen Encore NGS Library Systems for the Ion Torrent PGM. The library prep kit requires only 100 nanograms of DNA, and sequencing libraries can be created for a wide range of applications, including the option of 16-plex sequencing, according to the companies.


Bioo Scientific has launched the Nextflex ChIP-seq kit and barcodes, which uses the company's NanoQ low-input binding enzymes that have been designed for use with DNA input material of 10 nanograms or less. The kit also features enhanced adapter ligation technology, which improves the ligation enzymatic mix and can perform ligations with long adapters and better binding efficiencies, according to the company. The kit includes up to 96 unique adapter barcodes and is compatible with Illumina sequencing platforms.


The National Center for Biotechnology Information has released new data for build 135 of dbSNP, available here. The new release includes human data, as well as data from the bony fish, eucalyptus, fusarium, rubber tree, stickleback fish, and sweet cherry.


The Galaxy open-source, web-based platform for data-intensive biomedical and genetic research developed by researchers at Pennsylvania State University is now available via the Amazon Web Services cloud. Galaxy offers DNA-sequencing analysis software, genome-annotation databases, and storage capacity through a web-based portal so that researchers can search a variety of resources, combine data from independent queries, and visualize the results.

The Scan

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.

Study Reviews Family, Provider Responses to Rapid Whole-Genome Sequencing Follow-up

Investigators identified in the European Journal of Human Genetics variable follow-up practices after rapid whole-genome sequencing.

BMI-Related Variants Show Age-Related Stability in UK Biobank Participants

Researchers followed body mass index variant stability with genomic structural equation modeling and genome-wide association studies of 40- to 72-year olds in PLOS Genetics.

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.