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New Products: Life Tech's Ion AmpliSeq Panels

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Life Technologies has launched an Ion AmpliSeq BRCA1 and BRCA2 Panel as well as an Ion AmpliSeq Colon and Lung Cancer Panel.

The BRCA panel analyzes the coding regions of the BRCA1 and BRCA2 genes and was developed by researchers from Radboud University Nijmegen Medical Center and the University of Porto. The lung and colon panel analyzes over 500 mutations in 22 genes and was developed by eight institutions, including Radboud University Nijmegen Medical Center; Cancer Research Center of Mercogliano in Italy; the genetics and molecular biology division of pharmaceutical company Viollier in Switzerland; the University of Warwick in the UK; the Institut Gustave Roussy in France; the University Paris Descartes Center in France; and St James' Hospital in Dublin.

The Scan

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.

Study Reviews Family, Provider Responses to Rapid Whole-Genome Sequencing Follow-up

Investigators identified in the European Journal of Human Genetics variable follow-up practices after rapid whole-genome sequencing.

BMI-Related Variants Show Age-Related Stability in UK Biobank Participants

Researchers followed body mass index variant stability with genomic structural equation modeling and genome-wide association studies of 40- to 72-year olds in PLOS Genetics.

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.