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New Products: Life Tech's AmpliSeq Exome; Swift Biosciences' Accel-NGS; Genome-euro

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Life Technologies' Ion Torrent has launched AmpliSeq Exome kit. The kit uses 300,000 amplicons and can complete an exome capture in six hours with one hour of hands-on time and requires sample input of 50 nanograms, according to the company (see story, this issue).


Swift Biosciences is offering an early access program for its Accel-NGS Library Kit for Illumina's sequencing systems. According to the company, the kit enables PCR-free libraries with 250 nanograms of input DNA and is compatible with formalin-fixed paraffin-embedded tissue and damaged samples. Turnaround time is around 90 minutes.


The University of California, Santa Cruz Genome Browser has launched Genome-euro, a mirror site of the UCSC Genome Browser that is intended to serve users in Europe. The server is located in Universität Bielefeld Center for Biotechnology in Bielefeld, Germany, and is administered by UCSC. All functionality will be the same as on the US server.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.