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New Products: DNAStar's Lasergene; Bioo Scientific's NextFlex qRNA-seq; RefSeq 59

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DNAStar has released Lasergene 11, sequence assembly software that is available both in the Amazon Cloud and on desktop computers. Other improvements include the new application MegAlignPro and enhanced copy number variation analysis capability.


Bioo Scientific has released NextFlex qRNA-seq kit, which generates libraries equivalent to conventional RNA-seq libraries, but with the added feature of the company's proprietary molecular indexing technology. Prior to any PCR amplification steps, the DNA fragment ends are ligated to a pair of adaptors chosen at random from a total set of 9,216 molecular indices.


The National Center for Biotechnology Information has released version 59 of RefSeq, available via FTP.

The release includes genomic, transcript, and protein data available, as of April 29, 2013, and includes 39,040,745 records, 31,593,499 proteins, 3,579,371 RNAs, and sequences from 24,656 different organisms.

The Scan

Wolf Howl Responses Offer Look at Vocal Behavior-Related Selection in Dogs

In dozens of domestic dogs listening to wolf vocalizations, researchers in Communication Biology see responses varying with age, sex, reproductive status, and a breed's evolutionary distance from wolves.

Facial Imaging-Based Genetic Diagnoses Appears to Get Boost With Three-Dimensional Approach

With data for more than 1,900 individuals affected by a range of genetic conditions, researchers compared facial phenotype-based diagnoses informed by 2D or 3D images in the European Journal of Human Genetics.

Survey Suggests Multigene Cancer Panel VUS Reporting May Vary Across Genetic Counselors

Investigators surveyed dozens of genetic counselors working in clinical or laboratory settings, uncovering attitudes around VUS reporting after multigene cancer panel testing in the Journal of Genetic Counseling.

Study Points to Tuberculosis Protection by Gaucher Disease Mutation

A mutation linked to Gaucher disease in the Ashkenazi Jewish population appears to boost Mycobacterium tuberculosis resistance in a zebrafish model of the lysosomal storage condition, a new PNAS study finds.