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New Products: Dec 14, 2010


Beckman Coulter Genomics has launched its SPRIworks Fragment Library System III for automated library prep for Life Technologies' SOLiD. Earlier this year, the company launched library prep systems for the Illumina Genome Analyzer and the Roche 454 GS FLX. According to the company, the system can complete up to ten samples within three and a half hours. The system uses a color-coded method card and cartridges, so library construction for all three sequencing platforms can be done on one instrument with the appropriate method card and cartridges.

Complete Genomics
is now offering copy number variation and structural variation results as part of its CGA Service (see story, this issue), in addition to SNPs and small insertions and deletions. The company said the new data will be particularly useful in analyzing cancer genomes.

Ambry Genetics
has begun offering sequencing services on the Illumina HiSeq 2000. The company is a CAP-accredited and CLIA-certified commercial laboratory based in Aliso Viejo, Calif., and has been offering sequencing services on the Illumina platform since 2007.

Agilent Technologies has named EdgeBio as a certified service provider for its SureSelect Target Enrichment System. EdgeBio achieved SureSelect CSP status for the Life Technologies SOLiD 4 system. The SureSelect system includes target enrichment for user-specified genomic regions, the human kinome, the human X chromosome, and the human exome. In addition to the SOLiD, SureSelect can be used with both the Illumina and 454 platforms.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.