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New Products: Nov 2, 2010

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NuGen has released its Ovation WGA FFPE System and the Ovation RNA-Seq FFPE System, kits for amplifying genomic DNA from formalin-fixed, paraffin-embedded samples and preparing RNA-seq libraries from FFPE samples, respectively.

The kits are compatible for analysis using array-CGH, expression microarrays, and next-generation sequencing. According to the company, the Ovation kit is the only whole-genome amplification solution that provides enough yield to enable analysis by both aCGH and next-gen sequencing from a single reaction. In addition, the Ovation RNA-seq FFPE System is the first sample-preparation kit for transcriptome profiling with FFPE tissue, NuGen said.


BioNanomatrix launched its nanoAnalyzer 1000 System for DNA analysis at this week's American Society of Human Genetics meeting in Washington, DC. The system consists of a disposable nanochannel silicon-based device, analytical instrumentation, software, and reagents.

The company said it is developing a range of applications for the system including assessment of DNA sample quality for sequencing, assessment of DNA damage induced by environmental factors such as pollutants and radiation, methods for assisting researchers in genome assembly, and the identification and analysis of structural variation in genomic DNA. The company said that the system will be available to early-access customers in January.


The Scan

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.

Family Genetic Risk Score Linked to Diagnostic Trajectory in Psychiatric Disorders

Researchers in JAMA Psychiatry find ties between high or low family genetic risk scores and diagnostic stability or change in four major psychiatric disorders over time.

Study Questions Existence of Fetal Microbiome

A study appearing in Nature this week suggests that the reported fetal microbiome might be the result of sample contamination.

Fruit Fly Study Explores Gut Microbiome Effects on Circadian Rhythm

With gut microbiome and gene expression experiments, researchers in PNAS see signs that the microbiome contributes to circadian rhythm synchronicity and stability in fruit flies.