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New Products: Jul 19, 2011


Beckman Coulter Genomics has launched an automated target capture sequencing service. The service uses Agilent SureSelect target enrichment technology, Beckman Coulter's SPRIworks Fragment Library System for automated library construction, and the Biomek Laboratory Automation Workstation for liquid handling. Sequencing is performed on the Illumina GAII and HiSeq 2000 platforms.

Illumina has launched TruSeq Custom Enrichment kits to target genomic regions of interest ranging from 700 kilobases to 15 megabases of DNA. The kits use the same assay design as Illumina's TruSeq Exome Enrichment kits.

Illumina has also released an introductory version of DesignStudio, an online tool for the design of custom probes for multiple applications.

Along with the Ion 316 chip, Life Technologies' Ion Torrent has released a number of other products for use with the PGM sequencer:

The company has launched an early-access version of the Ion DNA Barcoding 1-16 kit for multiplexed sequencing of up to 16 samples per chip.

Also available are the Ion Library Quantitation kit, a TaqMan-based assay for femtomolar-level quantitation of Ion Torrent DNA libraries using qPCR, and the Ion Sphere Control kit for template bead quality control using the Qubit 2.0 fluorometer.

RefSeq release 48 is now available by anonymous FTP here.

The new release incorporates genomic, transcript, and protein data available as of July 10 and includes 18,162,534 records, 13,116,724 proteins, 2,634,630 RNAs, and sequences from 12,235 organisms.

The Scan

Octopus Brain Complexity Linked to MicroRNA Expansions

Investigators saw microRNA gene expansions coinciding with complex brains when they analyzed certain cephalopod transcriptomes, as they report in Science Advances.

Study Tracks Outcomes in Children Born to Zika Virus-Infected Mothers

By following pregnancy outcomes for women with RT-PCR-confirmed Zika virus infections, researchers saw in Lancet Regional Health congenital abnormalities in roughly one-third of live-born children.

Team Presents Benchmark Study of RNA Classification Tools

With more than 135 transcriptomic datasets, researchers tested two dozen coding and non-coding RNA classification tools, establishing a set of potentially misclassified transcripts, as they report in Nucleic Acids Research.

Breast Cancer Risk Related to Pathogenic BRCA1 Mutation May Be Modified by Repeats

Several variable number tandem repeats appear to impact breast cancer risk and age at diagnosis in almost 350 individuals carrying a risky Ashkenazi Jewish BRCA1 founder mutation.