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New Products: Jul 12, 2011

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Life Technologies has begun shipping the 316 chip for the Ion Torrent PGM, which, at 100 megabases, has a tenfold higher throughput than the previous 314 chip, according to the company (IS 6/28/2011). The PGM now also has run times of under eight hours. Additionally, the company is selling its 314 chip for $99, and plans to launch its 318 chip, which will have a throughput of 1 gigabase, in the fourth quarter of the year.


BGI has released an updated version of its Short Oligonucleotide Analysis Package, or SOAP, software. Improvements include increasing the speed of SOAP3 for aligning reads to a reference sequence, increasing the accuracy of SOAPdenovo for assembly, and increasing the speed and accuracy of SOAPIndel for calling long indels. The updated software is freely accessible via BGI's website here.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.