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New Products: May 31, 2011

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Life Technologies has launched its Life Technologies has launched its Ion Total RNA-Seq kit for transcript expression analysis on the Ion Torrent PGM. According to the company, the kit can analyze any type of RNA including rRNA-depleted total RNA, poly-A RNA, and small RNA. Additionally, it preserves strand information by aligning all mapped reads in the direction of transcription relative to the chromosomal strand.


Life Technologies also released its LifeScope bioinformatics software for analyzing next-gen sequencing data. The software has been optimized for the company's 5500 Series Genetic Analyzers. According to the company, LifeScope provides SNP detection, small RNA analysis, and other genomic-related analyses.

The Scan

Expanded Genetic Testing Uncovers Hereditary Cancer Risk in Significant Subset of Cancer Patients

In Genome Medicine, researchers found pathogenic or likely pathogenic hereditary cancer risk variants in close to 17 percent of the 17,523 patients profiled with expanded germline genetic testing.

Mitochondrial Replacement Therapy Embryos Appear Largely Normal in Single-Cell 'Omics Analyses

Embryos produced with spindle transfer-based mitochondrial replacement had delayed demethylation, but typical aneuploidy and transcriptome features in a PLOS Biology study.

Cancer Patients Report Quality of Life Benefits for Immune Checkpoint Inhibitors

Immune checkpoint inhibitor immunotherapy was linked in JAMA Network Open to enhanced quality of life compared to other treatment types in cancer patients.

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.