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New Products: Mar 1, 2011

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Bioo Scientific has launched NEXTflex DNA Sequencing kits and NEXTflex DNA Barcodes. The kits are designed to prepare single, paired-end and multiplexed genomic DNA libraries for sequencing using the Illumina Genome Analyzer and HiSeq 2000. According to the company, the kits use master mixed reagents and magnetic bead based cleanup, reducing pipetting and the number of steps in library preparation. The NEXTflex DNA Barcodes are adapter containing indexed sequences and enable multiplexing of up to 48 samples for a total of 384 reactions, according to the company. They are available in sets of 6, 12, 24, and 48 unique adapters.


Wrappers for next-generation sequencing tools and assembly packages are now available here in the Galaxy Tool Shed. The new tools support Velvet, Abyss, Phrap, Carpet, Newbler, Agile, Mimulus2, FastQC, and Lucy.



Accelerys
has released its NGS Collection for Pipeline Pilot. The software includes a range of algorithms, including methods for de novo assembly, mapping reads to reference sequences, identifying polymorphisms and structural variants, measuring RNA expression levels, and identifying transcription factor binding sites. It supports data from all major sequencing platforms including those from Illumina, Life Technologies' SOLiD, Roche 454, and others.
The Scan

Follow-Up Data Requests to Biobank Participants Ineffective, Study Finds

An effort to recontact biobank enrollees for additional information reports low participation in a new BMJ Open study.

Study Finds Widespread Transmission of Resistant Bacteria in Vietnam Hospitals

A sequencing study in The Lancet Microbe finds widespread transmission of drug-resistant Escherichia coli, Klebsiella pneumoniae, and Acinetobacter baumannii in two Vietnam ICUs.

Novel Brain Cell Organoids Show Promise for Autism Research

University of Utah researchers report in Nature Communications on their development of brain cell organoids to study SHANK3-related autism.

Study Finds Few FDA Post-Market Regulatory Actions Backed by Research, Public Assessments

A Yale University-led team examines in The BMJ safety signals from the US FDA Adverse Event Reporting System and whether they led to regulatory action.