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New Products: Jun 23, 2009


CLC Bio plans to release CLC Genomics Machine at a conference later this week, a "turnkey solution" for analyzing and visualizing next-generation sequencing data. The product consists of a hardware platform, several pre-installed software tools, including accelerated algorithms for next-generation sequencing data analysis, and an enterprise-level database.

The system includes a de novo assembly algorithm that enables assemblies of human and large plant genomes in a short time, according to the firm. Internal performance-benchmark studies have shown the system can generate a reference assembly of a human genome sequenced at one-fold coverage in about one hour. CLC Genomics Machine also includes other algorithms, like BLASTp, BLASTn, hmmsearch, hmmpfam, Smith-Waterman, and ClustalW.

Life Technologies division Applied Biosystems has launched the SOLiD Whole Transcriptome Analysis Kit, which enables the detailed characterization of all expressed RNA using the SOLiD sequencing platform. The kit, which combines Ambion reagents from Life Tech's Invitrogen brand with the SOLiD system, has already been used by researchers at the Beijing Institute of Genomics of the Chinese Academy of Sciences, according to ABI, to study expression profiles of multiple tissues and cells in human, mouse, rice, and microbes.

The Scan

Sick Newborns Selected for WGS With Automated Pipeline

Researchers successfully prioritized infants with potential Mendelian conditions for whole-genome sequencing or rapid whole-genome sequencing, as they report in Genome Medicine.

Acne-Linked Loci Found Through GWAS Meta-Analysis

Researchers in the European Journal of Human Genetics find new and known acne vulgaris risk loci with a genome-wide association study and meta-analysis, highlighting hair follicle- and metabolic disease-related genes.

Retina Cell Loss Reversed by Prime Editing in Mouse Model of Retinitis Pigmentosa

A team from China turns to prime editing to correct a retinitis pigmentosa-causing mutation in the PDE6b gene in a mouse model of the progressive photoreceptor loss condition in the Journal of Experimental Medicine.

CRISPR Screens Reveal Heart Attack-Linked Gene

Researchers in PLOS Genetics have used CRISPR screens to home in on variants associated with coronary artery disease that affect vascular endothelial function.