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LSU to Lead Killifish Sequencing Project

NEW YORK (GenomeWeb News) – Louisiana State University will lead a multi-partner study funded by the National Science Foundation to sequence and analyze the genome of the Atlantic killifish, a fish known for having a high tolerance for pollutants and for wide variations in temperature.

Because of its ability to survive in these difficult habitats the killifish is seen as a model for studies of environmental changes, climate change, and pollution. This research, funded with $165,000 from NSF, will create a sequence of the killifish genome that could be used as a reference against other killifish populations in order to discover the genes and genetic changes that underlie its pollution tolerance.

LSU is joined by partners at Washington University in St. Louis, Indiana University, the University of Miami, Woods Hole Oceanographic Institution, and Mount Desert Island Biological Laboratory.

Researchers at the University of Miami already have created a database on the expression of 1,000 genes for killifish and have used it to make discoveries about its pollution tolerance.

The Scan

For Better Odds

Bloomberg reports that a child has been born following polygenic risk score screening as an embryo.

Booster Decision Expected

The New York Times reports the US Food and Drug Administration is expected to authorize a booster dose of the Pfizer-BioNTech SARS-CoV-2 vaccine this week for individuals over 65 or at high risk.

Snipping HIV Out

The Philadelphia Inquirer reports Temple University researchers are to test a gene-editing approach for treating HIV.

PLOS Papers on Cancer Risk Scores, Typhoid Fever in Colombia, Streptococcus Protection

In PLOS this week: application of cancer polygenic risk scores across ancestries, genetic diversity of typhoid fever-causing Salmonella, and more.