Skip to main content
Premium Trial:

Request an Annual Quote

Life Tech Uses Diagenode Sonicator for Ion Torrent Shotgun Library Prep


This story was originally published March 7.

Life science research tool company Diagenode said last week that Life Technologies is using its Bioruptor sonicator to help prepare samples for the Ion Torrent PGM sequencer.

According to Belgium-based Diagenode, Life Tech is using the Bioruptor to shear DNA as part of a validated workflow to generate shotgun libraries for the Ion Torrent platform.

Separately, Life Tech said last month that it has partnered with Diagenode, and that the Bioruptor "has been extensively validated to quickly generate unbiased genomic fragments suitable in the creation of DNA libraries for the Ion PGM at an entry cost accessible to any laboratory."

Depending on the model, the Bioruptor has a list price between €10,600 and €17,000 ($14,800 and $23,700), according to Diagenode's website.

"While the Bioruptor sonicator has been recognized in several dozen journals for DNA shearing using multiple next-generation sequencing platforms, the selection as part of the validated workflow for the PGM system represents a major step forward in the recognition of the Bioruptor sonicator as a cost-effective, highly reproducible, and reliable solution," said Diagenode CEO Didier Allaer in a statement.

Diagenode, founded in 2004, has offices in Liège, Brussels, and in Denville, NJ. The company develops and sells instruments and reagents for life science research, in particular epigenetics, and for molecular diagnostics.

The Scan

Study Finds Sorghum Genetic Loci Influencing Composition, Function of Human Gut Microbes

Focusing on microbes found in the human gut microbiome, researchers in Nature Communications identified 10 sorghum loci that appear to influence the microbial taxa or microbial metabolite features.

Treatment Costs May Not Coincide With R&D Investment, Study Suggests

Researchers in JAMA Network Open did not find an association between ultimate treatment costs and investments in a drug when they analyzed available data on 60 approved drugs.

Sleep-Related Variants Show Low Penetrance in Large Population Analysis

A limited number of variants had documented sleep effects in an investigation in PLOS Genetics of 10 genes with reported sleep ties in nearly 192,000 participants in four population studies.

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.