Skip to main content
Premium Trial:

Request an Annual Quote

ISB Taps Complete Genomics for Disease Study

By a GenomeWeb staff reporter

NEW YORK (GenomeWeb News) – The Institute for Systems Biology has contracted Complete Genomics to sequence 615 complete human genomes as part of a study on neurodegenerative diseases, Complete Genomics said today.

Under the agreement, ISB will work with its academic partners to provide Complete Genomics with DNA samples from families in which multiple individuals are affected by neurodegenerative diseases.

The Mountain View, Calif.-based firm will perform the sequencing, assembly, and annotation and will provide ISB with a list of variations found in each genome. ISB will then conduct its own analysis, using family genetics and network studies to identify causal and modifying genes.

Complete Genomics has provided sequencing services to ISB before, sequencing 100 genomes for studies of Huntington's and other diseases in one effort last year, and sequencing four genomes as part of a study to find a causal gene in Miller syndrome.

All of ISB's work on these projects has been supported by the University of Luxembourg.

ISB President Leroy Hood said in a statement that the sequencing partnership with Complete Genomics enables the institute to "focus on data analysis and interpretation while avoiding major capital expense, pipeline building and technology development."

Financial terms of the agreement were not released.

The Scan

Rare Genetic Disease Partnership

A public-private partnership plans to speed the development of gene therapies for rare genetic diseases, Stat News writes.

Approval Sought for Alzheimer's Drug

The Wall Street Journal reports Eli Lilly has initiated a rolling submission to the US Food and Drug Administration to seek approval for its drug to treat Alzheimer's disease.

DNA Barcoding Paper Retracted

Science reports that a 2014 DNA barcoding paper was retracted after a co-author brought up data validity concerns.

Nature Papers Present Genomic Analysis of Bronze Age Mummies, Approach to Study Host-Pathogen Interactions

In Nature this week: analysis finds Tarim mummies had local genetic origin, and more.