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Einstein Center Reaps $17M from NCI for Infrastructure, Research Support

NEW YORK (GenomeWeb News) – The Albert Einstein Cancer Center (AECC) at Yeshiva University has received a $16.7 million grant from the National Cancer Institute to provide for support and infrastructure of its research programs, which involve a range of molecular, genomics, imaging, and related disciplines.

The funding will bolster research projects in five major areas at AECC, including studies of the tumor microenvironment and metastasis; stem cells, differentiation and cancer; experimental therapeutics; cancer epidemiology; and the biology of colon cancer, AECC said yesterday.

Supporting these research programs are 14 specialized shared resource facilities involving genomics, proteomics, biostatistics and bioinformatics, structural biology, transgenic mouse resource, and others. The new funding also would provide for a new shared resource, a cancer biospecimen and acquisition biorepository.

AECC's genomics facility provides a range of sequencing services , including massively-parallel assays for expression, resequencing and de novo sequencing; gene expression, exon, and SNP arrays from Affymetrix; SNP typing, CpG methylation, and gene expression from Sequenom; real-time PCR using Sybr Green and Taqman assays; DNA purification; pyrosequencing, and others.

The proteomics core lab provides protein identification services; analysis of small proteins; spatial localization of molecules by mass spectrometry; quantitative proteomics; confirmation of synthetic and recombinant molecules, and multiple reaction monitoring assays and pharmacokinetics, among others.

AECC said its location in the Bronx, New York, provides its researchers with access to samples from and studies of diverse ethnic and racial populations, making it "a national resource."

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