Skip to main content
Premium Trial:

Request an Annual Quote

Complete Genomics, SAIC-Frederick Team on Pediatric Cancer Study

By a GenomeWeb staff reporter

NEW YORK (GenomeWeb News) – Complete Genomics today said that it has joined SAIC-Frederick in a collaborative effort to identify and validate somatic mutations from 50 pediatric cancer cases from multiple research centers across the US.

SAIC-Frederick, a contractor working on behalf of the National Cancer Institute, will use Complete Genomics' sequencing and bioinformatics services to analyze 50 tumor-normal pairs. The partners hope the analysis will enable the identification of patterns of tumorigenesis, which could ultimately lead to improved diagnostics and treatments for pediatric cancer.

Mountain View, Calif.-based Complete Genomics will be paid $1.1 million for completing the project. The funding comes from the American Recovery and Reinvestment Act of 2009.

The collaboration is part of NCI's Therapeutically Applicable Research to Generate Effective Treatments (TARGET) Initiative, which seeks to use genomics technologies to rapidly identify valid therapeutic targets in childhood cancers.

The contract contains an option for SAIC-Frederick and Complete Genomics to sequence more than 500 additional NCI cases over an 18-month period.

The Scan

Study Tracks Responses in Patients Pursuing Polygenic Risk Score Profiling

Using interviews, researchers in the European Journal of Human Genetics qualitatively assess individuals' motivations for, and experiences with, direct-to-consumer polygenic risk score testing.

EHR Quality Improvement Study Detects Demographic-Related Deficiencies in Cancer Family History Data

In a retrospective analysis in JAMA Network Open, researchers find that sex, ethnicity, language, and other features coincide with the quality of cancer family history information in a patient's record.

Inflammatory Bowel Disease Linked to Gut Microbiome Community Structure Gradient in Meta-Analysis

Bringing together data from prior studies, researchers in Genome Biology track down microbial taxa and a population structure gradient with ties to ulcerative colitis or Crohn's disease.

Ancient Greek Army Ancestry Highlights Mercenary Role in Historical Migrations

By profiling genomic patterns in 5th century samples from in and around Himera, researchers saw diverse ancestry in Greek army representatives in the region, as they report in PNAS.