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CLC Bio, Roche, Danish Partners to Develop Methods for Sequencing, Analyzing FFPE Samples

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This story was originally published Sept. 9

CLC Bio, Danish genomics service provider Aros Applied Biotechnology, Roche, and Aarhus University Hospital are collaborating to develop a high-throughput platform for collecting, sequencing, and analyzing DNA extracted from formalin-fixed paraffin-embedded tissue samples, CLC Bio said this week.

Under the $5 million project, for which CLC and the Danish National Advanced Technology Foundation will each contribute half the funding, the partners plan to develop a platform for selecting appropriate FFPE samples, choosing an optimal sequencing technology, and assembling and analyzing the sequence data. The goal is to apply the platform in molecular diagnostics research and to re-analyze samples from preclinical trials where drugs have failed.

According to CLC Bio, the proposed platform will allow researchers to access more samples than those available through fresh tissue biobanks, and link the results to patient data.

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