NEW YORK (GenomeWeb) – A pair of studies appearing in Nature Neuroscience yesterday uncovered epigenetic changes associated with the development of Alzheimer's disease.

For the studies, the two research teams conducted epigenome-wide association studies to search for DNA regions that were differentially methylated in people who had Alzheimer's disease as compared to those without the disease. While the researchers uncovered nearly a dozen differentially methylated regions, both groups homed in on a hypermethylated region at the ANK1 gene.

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Mar
08
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Swift Biosciences

This webinar will discuss an optimized protocol for methyl-CpG binding domain sequencing (MBD-seq), which enables comprehensive, adequately powered, and cost-effective large-scale methylome-wide association studies (MWAS) of almost all 28 million CpG sites in the genome.

Mar
13
Sponsored by
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This webinar will share how clinical genetics labs can integrate cytogenetics and molecular data to assess abnormalities using a single sample on a single workflow platform.

Apr
03
Sponsored by
Dovetail Genomics

Proximity ligation technology generates multi-dimensional next-generation sequencing data that is proving to solve unmet needs in genomic research.