In Sequencing Study, Better Outcomes for Patients on Yervoy with Stable T-Cell Clonotypes | GenomeWeb

NEW YORK (GenomeWeb) — A study using next-generation sequencing to measure changes in T-cell receptor genes of patients treated with anti-CTLA-4 drugs like Bristol-Myers Squibb's Yervoy (ipilimumab) has found that patients whose T-cell landscape changed little from a pre-treatment baseline had improved survival compared to those who showed a drop in the T-cell clones that were most frequent prior to treatment.

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