The Klebsiella pneumoniae outbreak at the US National Institutes of Health's Clinical Center began with one patient in June of 2011. By the following January, it had infected 17 other patients, killing six of them.

With whole-genome sequencing and epidemiological techniques, NIH researchers led by Julie Segre were able to determine the route of K. pneumoniae transmission in real time, helping to contain the outbreak, as they published in Science Translational Medicine in August.

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