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In Print: Recent Pharmacogenomics Papers of Note: Aug 21, 2013

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Graft-versus-host disease biomarkers: omics and personalized medicine.
Paczesny S, Raiker N, Brooks S, Mumaw C.
Int J Hematol. 2013 Aug 20. [Epub ahead of print]


Immunohistochemistry reliably detects ALK rearrangements in patients with advanced non-small-cell lung cancer.
Han XH, Zhang NN, Ma L, et al.
Virchows Arch. 2013 Aug 18. [Epub ahead of print]


Targeted therapy; from advanced melanoma to the adjuvant setting.
Ahn A, Eccles MR.
Front Oncol. 2013 Aug 9;3:205.


Factors influencing organizational adoption and implementation of clinical genetic services.
Hamilton AB, Oishi S, Yano EM, et al.
Genet Med. 2013 Aug 15 [Epub ahead of print]


Cost-effectiveness of the 21-gene assay for guiding adjuvant chemotherapy decisions in early breast cancer.
Paulden M, Franek J, Pham B, et al.
Value Health. 2013 Jul-Aug;16(5):729-39.


Potential of Dihydropyrimidine Dehydrogenase Genotypes in Personalizing 5-Fluorouracil Therapy Among Colorectal Cancer Patients.
Teh LK, Hamzah S, Hashim H, et al.
Ther Drug Monit. 2013 Aug 12. [Epub ahead of print]


The development of dasatinib as a treatment for chronic myeloid leukemia (CML): from initial studies to application in newly diagnosed patients.
Hochhaus A, Kantarjian H.
J Cancer Res Clin Oncol. 2013 Aug 13. [Epub ahead of print]


Recommendations for reporting results of diagnostic genetic testing (biochemical, cytogenetic and molecular genetic).
Claustres M, Kožich V, Dequeker E, et al.
Eur J Hum Genet. 2013 Aug 14. [Epub ahead of print]


C-KIT Signaling in Cancer Treatment.
Stankov K, Popovic S, Mikov M.
Curr Pharm Des. 2013 Aug 12. [Epub ahead of print]


Decreased Expression of AZGP1 Is Associated with Poor Prognosis in Primary Gastric Cancer.
Huang CY, Zhao JJ, Lv L, et al.
PLoS One. 2013 Jul 23;8(7):e69155.


Targeting BRAF in Multiple Myeloma.
O'Donnell E, Raje NS.
Cancer Discov. 2013 Aug;3(8):840-2.


Early Results Promising for LKD378 in ALK-positive NSCLC.
[No authors listed]
Cancer Discov. 2013 Aug;3(8):OF5.


Prognostic Value of EGFR Mutation and ERCC1 in Patients with Non-Small Cell Lung Cancer Undergoing Platinum-Based Chemotherapy.
Yamashita F, Azuma K, Yoshida T, et al.
PLoS One. 2013 Aug 5;8(8):e71356.


CD44 Gene Polymorphisms in Breast Cancer Risk and Prognosis: A Study in North Indian Population.
Tulsyan S, Agarwal G, Lal P, et al.
PLoS One. 2013 Aug 5;8(8):e71073.


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The Scan

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While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.

TB Resistance Insights Gleaned From Genome Sequence, Antimicrobial Response Assays

Researchers in PLOS Biology explore M. tuberculosis resistance with a combination of sequencing and assays looking at the minimum inhibitory concentrations of 13 drugs.

Mendelian Disease Genes Prioritized Using Tissue-Specific Expression Clues

Mendelian gene candidates could be flagged for further functional analyses based on tissue-specific transcriptome and proteome profiles, a new Journal of Human Genetics paper says.

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.