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In Print: Recent PGx Papers

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Association Between Human Pain-Related Genotypes and Variability in Opioid Analgesia: An Updated Review.
Nielsen LM, Olesen AE, Branford R, et al.
Pain Pract. 2014 Sep 9. [Epub ahead of print]


Direct PCR: a new pharmacogenetic approach for the inexpensive testing of HLA-B*57:01.
Cascella R, Strafella C, Ragazzo M, et al.
Pharmacogenomics J. 2014 Sep 9. [Epub ahead of print]


Should mental health patients get pharmacogenomic testing?
Burns J.
Manag Care. 2014 Jul;23(7):28-30.


Pharmacogenomic Approach to Identify Drug Sensitivity in Small-Cell Lung Cancer.
Wildey G, Chen Y, Lent I, et al.
PLoS One. 2014 Sep 8;9(9):e106784.


High protein expression of EZH2 is related to unfavorable outcome to tamoxifen in metastatic breast cancer.
Reijm EA, Timmermans AM, Look MP, et al.
Ann Oncol. 2014 Sep 5 [Epub ahead of print]


Gene Variants in CYP2C19 are Associated with Altered In Vivo Bupropion Pharmacokinetics but not Bupropion Assisted Smoking Cessation Outcomes.
Zhu AZ, Zhou Q, Cox LS, et al.
Drug Metab Dispos. 2014 Sep 3. [Epub ahead of print]


Effect of CYP2C9-VKORC1 interaction on warfarin stable dosage and its predictive algorithm.
Li X, Liu R, Yan H, et al.
J Clin Pharmacol. 2014 Sep 4. [Epub ahead of print]


Genetic polymorphisms in candidate genes predict increased toxicity with methotrexate therapy in Lebanese children with acute lymphoblastic leukemia.
Zgheib NK, Akra-Ismail M, Aridi C, et al.
Pharmacogenet Genomics. 2014 Aug;24(8):387-96.


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The Scan

Billions for Antivirals

The US is putting $3.2 billion toward a program to develop antivirals to treat COVID-19 in its early stages, the Wall Street Journal reports.

NFT of the Web

Tim Berners-Lee, who developed the World Wide Web, is auctioning its original source code as a non-fungible token, Reuters reports.

23andMe on the Nasdaq

23andMe's shares rose more than 20 percent following its merger with a special purpose acquisition company, as GenomeWeb has reported.

Science Papers Present GWAS of Brain Structure, System for Controlled Gene Transfer

In Science this week: genome-wide association study ties variants to white matter stricture in the brain, and more.