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People in the News: Felix Frueh, Stephen Quake, Jack Davis

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Third Rock Ventures has hired Felix Frueh as an entrepreneur-in-residence. Frueh, past president of the Medco Research Institute, will "provide strategic input on new and existing portfolio companies with a particular focus on personalized medicine," the venture capital firm said in an announcement.

While at Medco, Frueh led many of the PBM's personalized medicine focused programs and clinical utility research on genomic tests. Frueh's departure from Medco followed the pharmacy-benefit manager's acquisition by Express Scripts earlier this year.

Before joining Medco, Frueh was associate director for genomics at the US Food and Drug Administration, where he was the head of the genomics review team in the Center for Drug Evaluation and Research and chaired the first interdisciplinary pharmacogenomics review group.


The Human Frontier Science Program Organization has awarded Stephen Quake the 2013 Nakasone Award for his work developing technologies in biophysics, biological automation, genome analysis, and personalized medicine. Quake is a professor of bioengineering and a Howard Hughes Medical Institute investigator at Stanford University. He is also a co-founder of Helicos Biosciences and Fluidigm.


BioMarker Strategies announced that Jack Davis, a co-founder and former CEO of Dianon Systems, has been named executive chairman of the company. Davis will serve as both chairman of the board and as the senior strategic management adviser for BioMarker Strategies. Before Dianon, Davis was division VP and general manager of the diagnostics products unit at Abbott Diagnostics.

The Scan

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.

Study Reviews Family, Provider Responses to Rapid Whole-Genome Sequencing Follow-up

Investigators identified in the European Journal of Human Genetics variable follow-up practices after rapid whole-genome sequencing.

BMI-Related Variants Show Age-Related Stability in UK Biobank Participants

Researchers followed body mass index variant stability with genomic structural equation modeling and genome-wide association studies of 40- to 72-year olds in PLOS Genetics.

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.