NEW YORK (GenomeWeb News) – Nanosphere reported after the close of the market Wednesday that its full-year revenues more than doubled and it trimmed its annual loss.

The firm also announced a management shakeup, which includes the naming of a new CEO and the replacement of several board members. Wall Street reacted negatively to the changes and a revenue forecast below expectations, sending the firm's shares tumbling 30 percent.

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In PNAS this week: rare variants linked to bleeding disorder, comparison of whole-exome and whole-genome sequencing, and more.

George Church tells The Sunday Times that his group has inserted some woolly mammoth genes into elephant cells.

A Scientific Reports editor resigns over a new policy at the journal allowing researchers to pay to fast track the peer review of their manuscripts, and poll.

The National Cancer Institute's Harold Varmus discusses the state of cancer research with the New York Times.