Epizyme, Abbott Developing CDx for Mixed Lineage Leukemia Drug

Epizyme and Abbott announced they are working together to develop a molecular diagnostic to accompany its investigational treatment for mixed lineage leukemia, EPZ-5676.

The drug, EPZ-5676, inhibits DOT1L histone methyltransferase. MLL, a subtype of acute myeloid leukemia and acute lymphoblastic leukemia, is caused by a translocation involving the MLL gene.

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