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Epizyme, Abbott Developing CDx for Mixed Lineage Leukemia Drug

Epizyme and Abbott announced they are working together to develop a molecular diagnostic to accompany its investigational treatment for mixed lineage leukemia, EPZ-5676.

The drug, EPZ-5676, inhibits DOT1L histone methyltransferase. MLL, a subtype of acute myeloid leukemia and acute lymphoblastic leukemia, is caused by a translocation involving the MLL gene.

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Oct
21
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Genomics is a key element in the potential of precision medicine to transform oncology. 

Oct
23
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This webinar will illustrate how single-cell methylation sequencing can be applied to gain significant insight into epigenetic heterogeneity in disease states, advancing cancer research discoveries.