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Ignyta Receives $1M Loan Facility

NEW YORK (GenomeWeb News) – Autoimmune diagnostics firm Ignyta today said that Silicon Valley Bank has provided it an additional $1 million capital term loan facility.

The new facility is on top of a previous $500,000 facility between the Ignyta and the bank arranged in June 2012. In January, Ignyta raised $5.5 million in Series B financing.

"Ignyta is well-capitalized to execute our ambition of developing an objective biomarker based test to help detect rheumatoid arthritis in its earliest stages," its Co-Founder and CEO Jonathan Lim said in a statement.

Earlier this week, the San Diego-based firm announced it would be working with Leiden University Medical Center to evaluate epigenetic signatures of patients with early synovitis and rheumatoid arthritis.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.