Originally published May 7.

Over the past several years there has been a major shift in cancer diagnostics from systems based on physical and histological findings to methods that assess and treat tumors based on the presence of distinct, targetable genomic mutations. A primary example of this shift is lung cancer, a disease that was long viewed as monolithic and with few treatment options, but now is known to have many molecular subtypes and genetic tests that can match patients with those subtypes to treatments.

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Biologists turn to environmental DNA sampling to determine whether elusive or invasive species are shedding DNA in a given area.

Rob Knight writes at Scientific American that microbiome studies are about to break out of the laboratory.

Harold Varmus, the director of the National Cancer Institute, has announced that he is stepping down after nearly five years.

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