Skip to main content
Premium Trial:

Request an Annual Quote

Genalyte Receives $500K SBIR Grant for Diabetes Assay Development

NEW YORK (GenomeWeb News) – Multiplex assay development firm Genalyte today announced it has been awarded a $500,000 Small Business Innovation Research grant to develop multiplexed diagnostic assays for the early detection and monitoring of type 1 diabetes.

The award is from the National Institute of Diabetes and Digestive and Kidney Diseases. The assays being developed will run on Genalyte's Maverick Detection System, which uses a silicon chip containing arrays of photonic ring sensors for the detection of multiple antibodies and other proteins from a single small sample.

The platform automates the washes, incubations, reagent processing, and other steps in the analysis process, Genalyte said.

It said that it will use the SBIR grant to build a multiplexed assay for detecting autoimmune response for known targets of type 1 diabetes, and then expand the assay capabilities to profile autoantibody response.

After the autoantibody panels have been developed and tested, San Diego-based Genaltye will validate them using samples from type 1 diabetes patients. Genalyte said it expects to collaborate on this phase of the project with researchers from the laboratory of the late George Eisenbarth at the Barbara Davis Diabetes Center of the University of Colorado School of Medicine.

"The pioneering work of the late Dr. Eisenbarth and others established that the development of type 1 diabetes is an incremental process, as rogue elements of the immune system over time compromise and eventually destroy the pancreatic islet cells that produce insulin," Martin Gleeson, CSO of Genalyte, said in a statement. "The unique capabilities of our Maverick multiplexed detection platform have the potential to provide researchers and clinicians with the tools to detect and track this process from a very early stage, when therapeutic intervention to interrupt the process could be feasible."

Genalyte was founded in 2007 and earlier this year it raised $11.8 million in a Series B financing round.

The Scan

White-Tailed Deer Harbor SARS-CoV-2 Variants No Longer Infecting Humans, Study Finds

A new study in PNAS has found that white-tailed deer could act as a reservoir of SARS-CoV-2 variants no longer found among humans.

Study Points to Benefits of Local Consolidative Therapy, Targeted Treatments in Cancer Care

In JCO Precision Oncology, researchers report that local consolidative therapy combined with molecularly targeted treatments could improve survival for some lung cancer patients.

Genetic Variants That Lower LDL Cholesterol Linked to Reduced Heart Disease Risk

Rare variants in two genes that lower LDL cholesterol are also associated with a decreased risk of coronary heart disease, according to a new JAMA Cardiology study.

Study Links Evolution of Longevity, Social Organization in Mammals

With the help of comparative phylogenetics and transcriptomics, researchers in Nature Communications see ties between lifespan and social organization in mammals.