In 2013, the top selling pharmacogenetically targeted drugs were well-known personalized medicine products, Herceptin and Gleevec.

Both of these drugs are slated to face generic competition soon, however, and when they do, drugmakers have newer agents in their pipelines to take their place. Meanwhile, across the PGx market, as new drugs are launched addressing smaller and smaller patient subsets, it raises the question whether any other personalized drugs will be able to match Herceptin or Gleevec's revenue success.

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