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The study will recruit up to 200 patients with active Crohn's disease or ulcerative colitis and sort them into high- and low-risk cohorts using the PredictSure IBD test. 

The firm is developing the test under a contract with the US Department of Health and Human Services' Biomedical Advanced Research and Development Authority.

The consortium is comprised of researchers from Inova, Roswell Park Comprehensive Cancer Center, the Mayo Clinic, and MD Anderson Cancer Center.

Among the study's goals is to identify molecular signatures that can distinguish idiopathic pulmonary fibrosis from interstitial lung disease.

The five-year funding commitment represents a 5 percent increase over the previous grant period for the rapidly growing archive of 3D protein structures.

The number of technologies to be assessed is vast, and ranges from liquid biopsies and molecular imaging to immunohistochemistry and RNA-seq.

The Hayward, California-based firm aims to tailor its NX One sample prep platform to isolate and detect cancer stem cells in urothelial cancer of the bladder.

The scientists aim to use single-cell analysis to investigate the role of variation in a gene called ID3 in vascular smooth muscle cells.

The project is part of the Human Cell Atlas, an international effort to build reference maps of all human cell types using single-cell analysis.

The NHGRI said it expects to fund between three and five research centers, as well as one coordinating center, over a five year period.

While the Oxford, UK-based company has focused on drug development partnerships to date, it is also keen to see uptake of genetic disease risk screening by the NHS.

The company's SpliceCore platform maps patient RNA sequencing data to a collection of over 5 million alternative splicing errors to pinpoint ones that cause disease.

The Genomics Research and Innovation Network has built an open-source system for querying genotype-phenotype databases at its member hospitals.

The institute will apply long-read sequencing to the NIH All of Us program and conduct pediatric sequencing for cancer and birth defect studies.

Acquired epilepsy is a form of the neurological disorder that results from other conditions such as stroke, infections, and traumatic brain injury.

The company aims to repurpose drugs by translating the mechanisms that allow hibernating animals to withstand the stresses of extended sleep.

Hallmarks of the genetic disease, which can result in life-threatening cardiac complications, include progressive weakness and loss of heart muscle.

Using 350 human genomes from different populations, the two centers plan to develop a multi-genome reference sequence that is as complete as possible.

The bill would provide additional funding to each NIH institute and center, and would follow a 5.4 percent budget increase received in fiscal 2019.

The award will fund optimization of the Hemopurifier exosome isolator, with an eye towards developing applications in cancer research and clinical care.

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According to NPR, an antibody-based test could identify people who were exposed to SARS-CoV-2 and either didn't develop symptoms or were misdiagnosed.

A sequencing analysis of New York City rats indicates they have adapted to the urban environment there, according to a recent preprint.

Ars Technica reports that a multicellular eukaryotic parasite has lost its mitochondria.

In Science this week: perspective piece says AI can accelerate drug discovery by using genomic and chemical data, and more.