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Two companies offering droplet-based single-cell RNA sequencing sample prep, 10x Genomics and 1Cellbio, have launched dual-indexed library preparation products.
Researchers have developed a method, called MemorySeq, to identify genes transcriptome-wide whose expression fluctuations persist for several cell divisions.
The Harvard spinout wants its instrumentation and reagent packages to ease the transition for labs interested in high-resolution imaging studies.
The company has developed a microscopy system that allows imaging of a full pathology slide in 21 channels with a single staining process and a rapid turnaround time.
Researchers from South Korea used 10x Genomics' scRNA-seq platform to also find type I IFN-driven inflammatory features in patients with severe influenza.
The single-cell RNA-sequencing analysis found that undifferentiated ependymomas are more likely to be linked to a poorer prognosis.
Transcriptomic and multi-omic data spanning more than 10,000 samples helped map "immunogenomic" interactions that may inform treatment outcomes and targets.
Analyzing transcriptome data from more than 1,000 cells from 74 embryos, a Johns Hopkins University-led team found aneuploid cells in 80 percent of embryos.
Researchers saw similar cell hierarchies and progenitor cell clusters when comparing single-cell RNA sequencing data for cells from glioblastoma tumors and developing brains.
The firms plan to collaborate with others in the field of regenerative medicine and cell therapy to expedite commercialization of the system.
The company will apply its single-cell RNA-seq analytics technology to three distinct cohorts in pursuit of new drug targets for inflammatory bowel disease.
A team of researchers in Germany investigated gene expression in airway cells of SARS-CoV-2 patients, finding increased interaction between epithelial and immune cells.
The SICILIAN algorithm, which uses statistical modeling to score candidate fusions in single-cell RNA sequencing data, is being used to map splice sites in individual tumor cells.
Investigators are planning to further validate specific applications, such as prediction of lung and lymphoma cancer subtypes, in independent sample sets.
Sex differences in muscle gene expression were further reduced with long-term endurance exercise, an international research team found.
Using Genotype-Tissue Expression project samples, researchers put together gene regulatory networks for 29 tissue types, uncovering extensive sex-related regulatory differences.
The Bay Area startup is offering a no-touch method to separate cell populations for downstream analysis in genomics and synthetic biology applications.
BioSkryb will now have an exclusive global license for clinical applications of primary template directed amplification technology.
The firms are targeting a compatible offering for single-cell gene expression screens following CRISPR-based editing, with applications in drug discovery.
Akadeum's microbubble technology and NanoCellect's Wolf cell-sorting platform will be integrated for high-quality single-cell sequencing of rare cell types.
A small, early-stage trial of a combination therapy for brain cancer reports favorable responses in two patients, according to the Guardian.
Nature News writes that viral genomic surveillance in the US faces systemic issues.
President Joe Biden is seeking an increase in federal spending, including higher budgets for the National Institutes of Health and Centers for Disease Control and Prevention.
In PLOS this week: sex-stratified genome-wide association study of chronic pain, sequencing data from Indigenous Mexican groups, and more.