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Researchers uncovered gene expression signatures that can predict whether someone may be protected by a malaria vaccine even before it is given.
At the Biology of Genomes virtual conference last week, several presentations focused on single-cell and spatial genomics data sets and how they could be complementary.
Research institutions in the US and Europe will lead the studies, which will explore different aspects of COVID-19 such as host immune response.
Using single-cell RNA sequencing, researchers identified cells in mouse and human prostate tissues that appear to help regrow the gland after prostate cancer treatment.
A single-cell "atlas" of pathologically normal breast tissue was presented by an MD Anderson Cancer Center representative at the AACR's online annual meeting this week.
The firm recently published a paper with its sibling company HiFiBio on antibody sequencing, but is looking to develop more applications.
Agilent, which co-led Mission Bio's 2018 $30 million Series B financing round, will comarket the Tapestri platform to cancer researchers in North America.
The researchers identified specific macrophage and conventional dendritic cell subsets as key mediators of cellular crosstalk in the tumor microenvironment.
A new paper outlines an upcoming effort to trace tumor development and trajectory in time and space using single-cell genetics and other genomic methods.
Tumors from patients who underwent full surgical resection had distinct molecular profiles from those treated with neoadjuvant chemotherapy.
Both studies emerged from the ongoing Human Cell Atlas project and could help scientists decide on the best approaches to use in various contexts.
The researchers said a functional investigation of the virus' unknown transcripts and RNA modifications will elucidate its life cycle and pathogenicity.
The protein-protein interactions tallied in the project are expected to inform future studies of biology and disease in various tissue and cell types.
The researchers applied their approach to study the heterogeneity of immune cells and adapted a visualization tool to analyze the data.
SkylineDx said that the firms will work together to develop predictive immunological signatures for BioInvent's lead therapy candidate.
The group will use IsoPlexis' single-cell proteomics platform to analyze immune cells from patients who have been diagnosed or recovered from COVID-19.
Researchers found that small-molecule inhibitors targeting oncogenic signal transduction or epigenetic regulation can alter specific 3D interactions in leukemia.
The team has begun analyzing additional analytes in HER2-positive breast cancer patients and will present preliminary results at AACR's annual meeting in May.
The Solna, Sweden-based company is currently expanding from offering in situ sequencing services to selling kits.
Researchers at the laboratory have developed a single-cell proteomics workflow capable of reproducibly quantifying 1,000-plus proteins per cell.
The Wall Street Journal reports that Russia's announcement of a coronavirus vaccine approval was met with concern as safety testing has not yet been completed.
New Scientist writes there aren't much data available on the accuracy of the two rapid COVID-19 tests the UK plans to roll out.
In PNAS this week: downstream effect of oncoprotein fusion, epigenetic changes influence tRNAs in colon cancer, and more.
Nature News reports that recent proposed changes to the US National Science Foundation have raised concerns about a shift away from the agency's focus on basic research.