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LSBC Hires Former Banker As President; CFO Retires

As part of a massive restructuring effort to curb costs and focus on its core database and intellectual property management businesses, Incyte Genomics has cut 56 positions at its Proteome subsidiary in Beverly, Mass., ProteoMonitor learned last week.

Proteome Systems has chosen IBM to provide the hardware and middleware for its proteomics discovery platform, Proteome Systems CEO Keith Williams said last week. An official announcement of the partnership is expected on November 20, he said.

In a sequel to its recent database deal with GeneFormatics, Celera Genomics will team with London-based Inpharmatica to develop a joint product built around Inpharmatica s structural bioinformatics technology and Celera s genomic data, the companies said last week. Notably, the effort marks the first time Celera has released its entire mammalian database to a third party for processing and structure/function annotation.

Breaking its silence on plans for its New Jersey facility, GeneProt said last week that it has purchased six Bruker Daltonics Ultraflex MALDI-TOF/TOF mass spectrometers for its new facility in North Brunswick, NJ, and an additional system for its Geneva laboratory.

AxCell Biosciences

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The US Patent and Trademark office has awarded AxCell Biosciences US patent 6,309,820 entitled “Polypeptides Having a Functional Domain of Interest and Methods of Identifying and Using Same.” The patent, with 9 claims, covers the company’s method for identi

As structural biology companies race ahead to obtain x-ray crystallography structures of promising drug targets, the biggest hurdle has traditionally been getting access to tunable x-ray sources at synchrotrons.

Bruker Daltonics and Biacore have agreed to jointly develop an instrument system for analyzing proteins that combines surface plasmon resonance (SPR) and mass spectrometry, the companies said last week.

For the first time in its 13 year history, the Genome Sequencing and Analysis Conference (GSAC) devoted a morning s plenary session to proteomics, which included talks by Denis Hochstrasser, co-founder of GeneProt, Scott Patterson, vice president of proteomics at Celera, and Dolores Cahill, a protein array researcher at the Max-Planck Institute of Molecular Genetics in Berlin.

AT A GLANCE
Name: Scott Patterson
Position: Vice President, Proteomics, Celera Genomics
Age: 39

Celera Adds geneformatics’ database to cds offerings

A patent and licensing dispute between Biosite and Xoma has disrupted a collaboration between Large Scale Biology Corporation (LSBC) and Biosite, and threatens to derail LSBC s efforts to develop protein microarrays, company officials told ProteoMonitor last week.

As a genomics-based biotech company, Millennium Pharmaceuticals has built some of its largest collaborations to date -- with companies such as Bayer and Aventis -- on the basis of its microarray and other gene expression technologies. But in recent months the Cambridge, Mass.-based company has indicated it is expanding its efforts in proteomics to augment its drug discovery arsenal.

In an effort to attract investors to its multi-dimensional liquid chromatography-based separation technology, Eichrom Technologies last week spun off its proteomics operations as a wholly-owned subsidiary called Eprogen.

Having outgrown the need for an in-house demonstration lab, Genomic Solutions announced earlier this month that it would spin off its costly proteomics research services business and form a new company, aptly named Proteomic Research Services (PRS).

Invitrogen plans to develop 2D gel electrophoresis technology for applications in proteomics using protein synthesis technology licensed from Gryphon Sciences, an Invitrogen spokesperson said last week.

Genomic Solutions

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The US Patent and Trademark Office has awarded Genomic Solutions US patent 6,302,159, entitled “Apparatus and method of carrying out flow through chemistry of multiple mixtures.” The patent covers technology developed by Genomic Solutions for its ProPrep and ProG

AT A GLANCE
Name: John M. Bergeron
Position: Chief Scientific Officer, Caprion Pharmaceuticals, Montreal, Quebec

Aspira Biosystems Wins $108K SBIR Grant to Develop Protein Chip

Position: CSO Large Scale Biology, Gaithersburg, MD
Age: 52
Prior Experience: Co-head of Molecular Anatomy Program, Argonne National Laboratory

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Master's and doctoral students in the UK call on funding groups to extend their grants for the duration of the disruption caused by the COVID-19 outbreak, the Guardian reports.

Squid can make edits to their RNA within the cytoplasm of their axons, Science News reports.

The Chan Zuckerberg Initiative is putting $25 million toward COVID-19 treatment research, according to the Verge.

In Science this week: researchers engineer version of Cas9 that is nearly PAM-less, and more.