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When a group of renowned analytical chemists and bioinformaticists founded systems biology startup Beyond Genomics last March, it was clear proteomics would play a role in the company s vision to integrate genetic, protein, and metabolite data into a computational model of how mammalian organisms function.

At a ceremony earlier this month featuring guided tours and a discussion moderated by Eric Lander, MDS Proteomics officially unveiled its new global headquarters and functional proteomics center in Toronto.

Name: Stanley Hefta
Position: Executive Director of Proteomics, Bristol- Myers Squibb

Bruker AXS Files Registration for Initial Public Offering

Breaking its silence on plans for its New Jersey facility, GeneProt said last week that it has purchased six Bruker Daltonics Ultraflex MALDI-TOF/TOF mass spectrometers for its new facility in North Brunswick, NJ, and an additional system for its Geneva laboratory.

AxCell Biosciences


The US Patent and Trademark office has awarded AxCell Biosciences US patent 6,309,820 entitled “Polypeptides Having a Functional Domain of Interest and Methods of Identifying and Using Same.” The patent, with 9 claims, covers the company’s method for identi

Name: John C. Norvell
Position: Director of the NIGMS research training program and of the NIGMS Protein Structure Initiative

LSBC Hires Former Banker As President; CFO Retires

As part of a massive restructuring effort to curb costs and focus on its core database and intellectual property management businesses, Incyte Genomics has cut 56 positions at its Proteome subsidiary in Beverly, Mass., ProteoMonitor learned last week.

Proteome Systems has chosen IBM to provide the hardware and middleware for its proteomics discovery platform, Proteome Systems CEO Keith Williams said last week. An official announcement of the partnership is expected on November 20, he said.

In a sequel to its recent database deal with GeneFormatics, Celera Genomics will team with London-based Inpharmatica to develop a joint product built around Inpharmatica s structural bioinformatics technology and Celera s genomic data, the companies said last week. Notably, the effort marks the first time Celera has released its entire mammalian database to a third party for processing and structure/function annotation.

A patent and licensing dispute between Biosite and Xoma has disrupted a collaboration between Large Scale Biology Corporation (LSBC) and Biosite, and threatens to derail LSBC s efforts to develop protein microarrays, company officials told ProteoMonitor last week.

As structural biology companies race ahead to obtain x-ray crystallography structures of promising drug targets, the biggest hurdle has traditionally been getting access to tunable x-ray sources at synchrotrons.

Bruker Daltonics and Biacore have agreed to jointly develop an instrument system for analyzing proteins that combines surface plasmon resonance (SPR) and mass spectrometry, the companies said last week.

For the first time in its 13 year history, the Genome Sequencing and Analysis Conference (GSAC) devoted a morning s plenary session to proteomics, which included talks by Denis Hochstrasser, co-founder of GeneProt, Scott Patterson, vice president of proteomics at Celera, and Dolores Cahill, a protein array researcher at the Max-Planck Institute of Molecular Genetics in Berlin.

Name: Scott Patterson
Position: Vice President, Proteomics, Celera Genomics
Age: 39

Celera Adds geneformatics’ database to cds offerings

Name: John M. Bergeron
Position: Chief Scientific Officer, Caprion Pharmaceuticals, Montreal, Quebec

Aspira Biosystems Wins $108K SBIR Grant to Develop Protein Chip

As a genomics-based biotech company, Millennium Pharmaceuticals has built some of its largest collaborations to date -- with companies such as Bayer and Aventis -- on the basis of its microarray and other gene expression technologies. But in recent months the Cambridge, Mass.-based company has indicated it is expanding its efforts in proteomics to augment its drug discovery arsenal.


The New York City Police Department will be removing DNA profiles from a local database if they are from people who were never convicted of a crime, the New York Times reports.

Science reports that accusations of sexual assault against a microbiome researcher has also led to questions about his academic certifications.

Wired reports that researchers are analyzing the DNA fish leave behind in water to study their populations.

In Science this week: comprehensive cellular map of the human thymus, evidence of admixture between the ancestors of Neanderthals and Denisovan and a 'superarchaic' population.