Analyzing proteins for posttranslational modifications using mass spectrometry is a tricky business, usually requiring many rounds of analysis of peptide fragments. Wouldn t it be nice to be able to stick an entire protein into the mass spec and get out all of the modifications? Subscribers: click headline for more.
Bowing to pressure from its UK-based rival, GeneProt has agreed to pay $1 million in cash and equity to Oxford GlycoSciences for the right to license two patents covering a procedure for separating and analyzing proteins using an automated 2D gel electrophoresis platform, the companies said last week. Subscribers: click headline for more.
Despite cash-flow problems and the termination of its research partnership with antibody-manufacturer Biosite, Large Scale Biology still has plans to release antibody chips for use in commercial research by early 2003, LSBC CEO Bob Erwin told ProteoMonitor last week. Subscribers: click headline for more.
Hybrigenics has signed a research agreement with Mindsense Biosystems, marking the first partnership under which the Paris-based company will own rights to develop therapeutics from the resulting data, Hybrigenics said last week. Subscribers: click headline for more.
If you thought microarrays were tiny, brace yourself for the next small thing: nanoarrays. In last week s Sciencexpress, Chad Mirkin and colleagues from Northwestern University and the University of Chicago describe their protein arrays with feature sizes of 100 to 350 nanometers, producing an array about 200,000 times more dense than the yeast proteome array most recently reported in the literature.. Subscribers: click headline for more.
Motivated by the desire to improve upon the ICAT reagent technology, Andrew Emili and his colleagues at the University of Toronto have devised a tagging technique for performing de novo peptide sequencing and quantitative protein profiling experiments that they claim is cheaper and less complicated than its more established cousin.. Subscribers: click headline for more.
While HUPO picks the brains of experts for ideas on how to coordinate large-scale partnerships between academia and industry, a consortium of nine academic groups and three biotechnology companies in Germany has picked the brain for a project that aims to develop and evaluate new proteomics technologies. . Subscribers: click headline for more.
Last month, Cellzome and MDS Proteomics unveiled their technologies for large-scale analysis of cellular protein complexes in competing articles published back-to-back in Nature Subscribers: click headline for more.
The National Human Genome Research Institute, and other NIH institutes are releasing a request for applications this week for a program to fund a genome-wide protein sequence database, NHGRI said Jan. 29 Subscribers: click headline for more.
In another sign that Bruker Daltonics MALDI TOF-TOF mass spectrometer may be beating out Applied Biosystems version of the instrument, Roche said last week that as part of a technology development agreement it intended to trade in at least 10 of its 12 Bruker-built MALDI TOFs for next-generation Bruker TOF-TOFs over the next year Subscribers: click headline for more.