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The five-year initiative aims to collect and disseminate genomic data on 1 million people with Alzheimer's disease or who are at risk for the condition.
This superarchaic hominin population split from other humans about 2 million years ago and interbred with the ancestors of Neanderthals and Denisovans about 700,000 years ago.
The researchers' findings suggest that methylation at those sites might have their effect on lung function through its effect on smoking behaviors.
The consortium will gather Nigerians' genomic, phenotypic, and clinical data in six geopolitical regions to study non-communicable and infectious diseases.
Though 10x will phase out its linked reads technology, it plans to introduce targeted RNA-seq for Chromium and FFPE sample compatibility for Visium.
University of Manchester and University of Cambridge researchers found SNPs in genes involved in cell survival, estrogen metabolism, and transcriptional control.
Researchers combined imaging mass spectrometry and genomic data to identify the cell types present in more than 480 breast cancer samples.
Bruker has postponed reporting of its final Q4 and full-year 2019 results, but reported preliminary Q4 revenues of $599.9 million and full-year revenues of $2.07 billion.
The program will aim to develop and evaluate genomics and informatics tools to improve the diagnosis, treatment, and prevention of disease.
With data from UK Biobank participants, investigators identified dozens of snoring-related genetic loci and links to traits such as weight, smoking, and sleep apnea.
The study characterized aspects of the tumor immune landscape, including immunogenic alterations, neoantigens, and the immune microenvironment.
A high genetic risk score was associated with increased risk of developing type 2 diabetes in both a US and a Danish cohort of women with gestational diabetes.
A large genome-wide association study that included more than 400,000 UK Biobank participants led to 69 new or known loci associated with 25-hydroxyvitamin D levels.
Understanding the genetic causes of hypercholesterolemia could provide prognostic information to help treat patients, the researchers said.
The findings suggest that the ancestors of modern West Africans interbred with a hominin population that split from the modern human lineage before Neanderthals did.
Investigators tracked down a methylation signature in blood that corresponded with features found in postmortem brain samples from schizophrenia cases.
The findings, published this week in mSystems, could help studies examining the role of microbes in aging and aging-related diseases.
Fourth quarter revenues of $32.4 million were in line with previously reported preliminary revenues and ahead of the Wall Street estimate of $30.8 million.
All three methods build on the use of methyltransferases to mark accessible regions of the genome, using nanopore sequencing to detect the modifications.
Nuclease-deficient mouse models revealed a stepwise process for the transformation of intact DNA molecules into circulating cell-free fragments.
Kelvin Droegemeier, the director of the White House Office of Science and Technology Policy, is the new acting director of the US National Science Foundation.
An opinion piece at the Guardian discusses the state of SARS-CoV-2 testing in the UK.
Wired reports the University of California, Berkeley's Innovative Genomics Institute has transformed itself into a diagnostic lab to run SARS-CoV-2 tests.
In Nature this week: direct-capture Perturb-seq approach for combinatorial single-cell CRISPR screens, potential uses of genome-editing in breeding crops, and more.