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Sex differences in muscle gene expression were further reduced with long-term endurance exercise, an international research team found.
Using Genotype-Tissue Expression project samples, researchers put together gene regulatory networks for 29 tissue types, uncovering extensive sex-related regulatory differences.
The Bay Area startup is offering a no-touch method to separate cell populations for downstream analysis in genomics and synthetic biology applications.
RNA-seq of ascites from ovarian cancer patients uncovered shared inflammatory programs and suggested a JAK/STAT pathway inhibitor has antitumor activity.
Study subjects of both sexes who had low germline mutation rates lived nearly five years longer than individuals with high mutation rates.
Christiana Care researchers have identified a unique protospacer adjacent motif site that allows them to knock out the NRF2 gene in tumor cells while leaving normal cells alone.
The work suggests mass spec can more accurately assess levels of immunotherapy targets like PD-L1 than conventional clinical approaches.
The researchers covered 100 organisms from a wide range of taxonomies, allowing for large-scale cross comparisons of species at the protein level.
Investigators identified an inbred individual who appeared to be part of a high-status group buried in lavish tombs during the Neolithic period.
Antibody products manufactured by Bethyl will be verified on Fluidigm's Hyperion imaging system and subsequently offered to Fluidigm's customers.
A meta-analysis including 1.4 million people from five ancestral groups identified 318 novel variants associated with type 2 diabetes and related vascular outcomes.
While there were a few new mass spectrometry instrument introductions, vendors focused primarily on software and sample separation advances.
Sequences from 20 Neolithic and Iron Age individuals in sub-Saharan Africahelped retrace regional interactions between forager, pastoralist, and farming groups.
Polygenic risk scores have the potential to impact cancer screening, autoimmune disease testing, and therapeutics development, but more diverse data is needed.
Researchers used a high-throughput proteomic platform to find patterns of protein expression that could identify patients at risk of developing severe infections.
A method called microbiome-derived metabolism screening highlighted drug alterations after exposure to personalized gut microbe collections.
The framework is meant to guide healthcare providers in facilitating prostate cancer genetic testing in a timely and responsible way, the researchers said.
The GWAS of more than 200,000 Japanese individuals across 42 diseases identified 25 novel loci shared between Japanese and European populations.
The Phase 2 grant is for work the company is doing to analyze the proteomic responses of immune cells in patients with Alzheimer's and related conditions.
The company is developing a mass spec-based instrument for the detection and identification of airborne opioids, microbes, and toxins in real-time.
Researchers have developed a robotic lab assistant, the Verge reports.
CBC News reports Canada's Supreme Court is to rule on the constitutionality of the country's genetic non-discrimination law today.
The Associated Press reports the World Health Organization is sending experts to China to investigate the animal source of SARS-CoV-2.
In Science this week: atlas of affected cell populations in idiopathic pulmonary fibrosis, and more.