Starting in early 2019, Yale plans to sign up at least 100,000 patients to analyze their genomes and EHR data for research and return of clinically actionable results.
After an unsuccessful commercialization attempt more than a decade ago, the company is bringing a revamped version of the ion mobility technology to market.
According to the researchers, this is one of the first successful such predictions and could aid the understanding of links between gene expression and metabolism.
The researchers are studying the molecular links between bile duct cancer and liver fluke infection, and testing a vaccine to protect against infection.
In a pair of studies, Weizmann Institute of Science researchers examined the effect of probiotics on healthy gut microbiomes and ones treated with antibiotics.
PNNL researchers have developed a targeted mass spec approach that they said could enable single-cell measurement of the 2,500 most abundant human proteins.
The enzymes enable rapid labeling without the use of toxic reagents like hydrogen peroxide, which has limited the use of proximity labeling in living samples.
These differentially variable positions appear to implicate stress response in rheumatoid arthritis development and possibly in other autoimmune conditions.
A workflow developed by the company along with Max Planck researchers demonstrates the system's potential for enabling high-throughput proteomic experiments.
The program was established to support the development and dissemination of functional genomic tools and techniques for genome manipulation in model organisms.
The method combines stable isotope dimethyl labeling with DiLeu isobaric tagging and allows multiplexing of up to 24 samples in a single mass spec experiment.
The ability to effectively use FFPE tissue opens up a large number of clinical samples for analysis, many with quality data on patient demographics, treatment, and outcomes.
An Australian-led team has generated a draft genome assembly of the invasive cane toad in hopes it will help in population control, the Sydney Morning Herald reports.
The New York Times reports that the US Department of Defense has implemented about half the recommendations made to improve safe handling of dangerous agents.
