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More articles about Biomarker Discovery & Validation

UK researchers have detected RNA biomarkers in extracellular vesicles that are potentially correlated to aggressive mesenchymal glioblastoma cells.

The companies will use Freenome's platform to identify cancer patients who are most likely to respond to treatment with ADC's loncastuximab tesirine.

The drug developer said that the biomarker panel will form the basis of a planned point-of-care test for acute respiratory distress syndrome.

The firm is developing a biomarker panel to detect mutations in mesenchymal cells, with the goal of guiding drug treatment and improving earlier patient intervention.

The international firm is one of several pharmaceutical companies emphasizing new single-cell technologies to improve existing drugs and find new ones.

The deals follow a pair of other recent acquisitions by Precision for Medicine in the artificial intelligence technology and biomarker analysis fields.

The partners are working under NIAAA grants to identify genetic markers to help predict response to the drug acamprosate, which is used as a treatment for alcoholism.

A SUNY Upstate team identified potential PD biomarkers in patients' oral microbiomes, which may lead to a saliva-based assay for early-stage disease. 

A proof-of-principle study suggests metabolite clusters may differ in non-small cell lung cancer patients depending on tumor type, disease stage, and overall survival trajectory.

 

Celsius Therapeutics uses single-cell genomic sequencing and informatics to discover new therapies for autoimmune disease and cancer.

The company develops assays and reagents for tissue-based biomarker research and discovery including its UltiMapper line of multiplexed assays.

The firm is validating two biomarkers that it hopes will stratify patients for its investigational drug for pediatric minimally verbal autism.

Tissue-agnostic drug development approaches have their own set of scientific and financial considerations, but some drugmakers are taking on those challenges.  

The company, which is also backed by Health Innovation Manchester, aims to expedite the commercialization of biomarkers into new diagnostic tests.

Canopy aims to use Zellkraftwerk's microfluidic cell-capture technology to further develop drug-development research and biomarker discovery.

The South Korean companies have also agreed to work together on the development of exosome-based biomedical products including diagnostics and therapeutics.

The companies will combine their respective technologies to create a biomarker and companion diagnostic development service for pharmaceutical customers.

Investigators found methylation models in conserved ribosomal DNA from mice also showed promise as age predictors in canine and human samples.

Researchers identified PTEN mutations, MAP kinase pathway alterations, and other features linked to anti-PD-1 response in individuals with the brain cancer.

The company is working with partners to identify new biomarkers and treatments as well as to collect utility evidence for its current coaching model.

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Politico reports that the NYPD DNA database has grown since it announced it would be removing profiles from it.

Forbes reports that a structural biology lab at Oxford University studying the coronavirus was hacked.

Science reports that a Dutch research funding agency is combating a ransomware attack.

In Science this week: set of 64 haplotype assemblies from 32 individuals, and more.