More articles about Autoimmune Disease

A University of Colorado School of Medicine-led team reported 23 new loci associated with vitiligo susceptibility.

The test is based on a biomarker signature that consists of a core set of 31 genes associated with endotoxin tolerance in sepsis patients.

The company said this study marks the first time circulating RNA has been concretely linked to IFN dysregulation in lupus patients.

After reporting FY2016 revenues below market expectations, Myriad discussed plans to increase sales of Prolaris, Vectra DA, EndoPredict, GeneSight, and myChoice HRD.

Despite the historical adoption and reimbursement challenges for PGx testing firms, Myriad said it would try to achieve value-based pricing for Assurex's GeneSight test.

The firm is investing in studies that use its multiplex microarray platform to monitor lupus disease activity and traumatic brain injury response.

A Winthrop-University Hospital team showed that demethylated circulating cell-free DNA from dying oligodendrocytes is a biomarker for relapsing-remitting MS.

The meta-analysis drew on studies conducted in both European and Chinese populations, and hinted at why lupus may be more common among East Asians.

Firalis is developing an assay based on HTG's EdgeSeq platform to identify rheumatoid arthritis patients likely to respond to anti-TNF-alpha therapies.

An international research team studied how genetic factors control immune cell response to pathogens in healthy individuals. 

Certain bacterial species appear more common in gut microbiomes of individuals with MS, coinciding with inflammation-related gene expression in host blood.

The collaboration will use Transplant Genomics' TruGraf test for post-kidney transplant monitoring to try to personalize immunosuppression therapies.

The company now offers three CE-marked autoantibody assays — for BICD2, Scl70, and CENP-B — that can be used for clinical management of the condition.

A team of scientists and entrepreneurs is trying to build a company around a dataset from a large multi-omics clinical study funded by Genome Canada.

The funding will support development of tests that detect cell-free DNA methylation patterns indicative of disease in specific tissues of the body.

The company said it has enlisted 23 academic and medical institutions to supply patient samples that will support the validation and launch of its tests.

Researchers identified a common variant in a long non-coding RNA that may contribute to inflammation seen in patients diagnosed with celiac disease. 

A mutation uncovered in a Belgian family through genetic analysis disrupts pyrin protein regulation to lead to an autoinflammatory disease.

The firm has not disclosed the specific disease the test will address but has determined this space represents the best opportunity for its array technology.

The new study in NEJM describes six families that share a disorder caused by mutations in IKAROS, a protein that plays a role in immune cell development. 

Pages

The New York Times profiles 23andMe's Anne Wojcicki and describes how she bounced back from a bad year.

Fotis Kafatos, the founding president of the European Research Council, has died, according to the Associated Press.

In PLOS this week: genomic analysis of honeybee disease, microRNA profiles of people with lupus nephritis, and more.

The Verge's Angela Chen tried out a gene test for fitness advice, but didn't learn much new information.