The researchers uncovered disease-linked genes that are expressed in certain cells and disease stages and discovered various gene expression modules.
Researchers focused in on strong candidate genes in schizophrenia with brain anatomy, brain activity, and behavioral screens on a large set of zebrafish mutants.
The researchers plan to study how infectious pathogens influenced the evolutionary history of certain mental and neurological disorders.
With available brain data, researchers came up with expression prediction models for finding new schizophrenia-related genes in a larger case-control set.
The findings implicated immune response, lipid metabolism, tau binding proteins, and amyloid precursor protein metabolism pathways in disease risk.
Free genetic testing on a broad gene panel is available to children, from birth to five years old, if they've had an unprovoked seizure.
Researchers used a genome-wide association study to identify seven loci associated with ASD and other conditions, along with five loci linked to ASD alone.
The five-year deal, which is being funded by UCB, will focus in particular on epilepsy patients who do not respond to currently available treatments.
Researchers prioritized schizophrenia risk SNPs from genome-wide association studies and used functional genomics to find transcription factor-disrupting risk SNPs.
Two independent teams described potential roles for gut microbes, and the compounds they produce, in schizophrenia, depression, and mental quality of life.
The findings underscored links between depression and other conditions and suggested a number of potential new targets for treatment with existing drugs.
The ALS Association is committing $3.5 million, including a $1 million commitment from its Greater New York chapter, while the Tow Foundation is contributing $2.5 million.
Polygenic risk scores for depression, bipolar disorder, and schizophrenia are associated with depression in a general population cohort.
Using UK Biobank and 23andMe data, researchers found 352 loci influencing sleep time preferences, including sites near brain- and retina-expressed genes.
Lineagen hopes to use PWNHealth's consumer-oriented model to expand access to its testing services for developmental delay and autism spectrum disorder.
Further analysis linked the new loci to genes implicated in immune-related tissues and cell types, as well as to lipid-related processes, suggesting their involvement in disease development
Data from the GUIDED study will be central to commercial payor discussions, a Medicare LCD reconsideration request, and eventually expansion into the primary care market.
Researchers found 253 candidate disease genes, based on 10,927 exomes from patients with autism spectrum disorder, developmental delay, or intellectual disability.
Using data for almost 10,900 Latino individuals with diverse ancestry, investigators identified distinct patterns for risky or protective APOE variants.
The firm is seeking damages and various injunctions, citing 11 different counts of fraud, breach of contract, tortious interference, and unfair competition.
The nonprofit Biden Cancer Initiative is suspending its operations, according to the Associated Press.
Researchers examine how white nationalists handle personal genetic ancestry results that conflict with their racist worldview, the New York Times reports.
NPR speaks with research participants before and after they learn their APOE E4 status, which affects their risk of developing Alzheimer's disease.
In PLOS this week: genetic characterization of Toxoplasma gondii strains, Crimean-Congo Hemorrhagic Fever Virus uncovered in Sudan, and more.